Multiparameter test for the differential diagnostics of COVID-19

What are the critical predispositions for a severe progression of COVID-19? Could it be possible to predict the progression by using a rapid test and thus enable differential diagnostics and treatment of COVID-19 patients?

The project BEAD-Dx addresses exactly these questions. To answer them, the project aims to develop an assay that not only measures the characteristic SARS-CoV-2 antibodies but also other biomarkers that are relevant to the immune status of each patient. This assay will be adapted from an existing Multiplex-Assay, which is based on modified beads with peptides or proteins and measurement of fluorescence intensity. A rapid and simultaneous analysis of various relevant parameters should facilitate the differential diagnostics during a COVID-19 infection and support physicians in the assessment, classification, and prognosis of disease progression and eventually treatment decisions

Project partners

PolyAn GmbH 

Medipan GmbH

Universität Potsdam, AG Molekulare Bioanalytik

The project was funded by the Federal Ministry of Education and Research.

Grant Number: 03COV23C

Further Projects



Development of a sensitive antigen-based rapid test for the diagnostic of COVID-19


Development of a sensitive DNA-based rapid test for the diagnostics of COVID-19


Epidemiological investigation on peptide signatures, immunity, genetic predisposition as well as changes in SARS-CoV-2.


Appropriate and high quality study material is essential for the development of diagnostic tests.


Can the identification of immunotopes serve as a basis for e.g. diagnostic tests?